
I consider my blog post at times as being written in Abstract
Understanding Abstract Art & Writing – Search
Understanding and appreciating abstract art can seem daunting at first. Here are some tips to help beginners navigate and connect with abstract works:
- Keep an Open Mind: Approach abstract art without expectations. Allow yourself to be surprised.
- Feel, Don’t Analyze: Initially, focus on how the artwork makes you feel rather than trying to figure out what it means.
- Learn About the Artist: Understanding the artist’s intent and background can provide insights into their work.
- Engage with the Art: Spend time with the artwork. View it from different angles and distances. Notice the use of color, shape, and texture.
The Link Between Proteins, Alzheimer’s and Parkinson’s Diseases – YouTube
Wrong title: it is not about “proteins”, it’s about the tau-protein, which gets dubbed as a “cause”. …while it is just a steppingstone in a causal chain. I was wanting to learn how proteins in the diet cause neurological problems. What if the body starts making tau and beta proteins to protect the brain against inflammation caused by junk foods, microbiome dysbiosis, and glycation by refined sugars?
What Does Alzheimer’s Do to the Human Brain?
Metabolic proteins to empower the study of Parkinsons is where the neural systems become embedded in traits of neural resting disintegration. Too much of not enough mental activity and Parkinsons is yours to battle.
Check Out: “Mind-Body Medicine to Build Stress Resilience” here: https://youtu.be/OIRT2gFPHOE
Maybe it is not the intense exercise but the diversion of imbibed protein into the muscles following the intense exercise.
Interesting – she mentioned the football players head injuries but who typically supplement with lots of protein to build muscle mass. Could it be the increased protein rather than head injuries causing more brain disease?
Gut microbiota acts like an auxiliary liver, study finds
But that’s only if you have the predisposition or genetic mutation that this can occur… Unfortunately, these amino acids always come together. Especially in a protein powder… So I guess avoid the processed protein powders and just eat the whole real food. So that it will be perfectly balanced by nature.
Some research reports lower intake of protein in diet is better overall for longevity especially when limiting it to under 50 to 60 yrs of age. But after 60 research indicating better to increase protein amount. Maybe limiting protein in younger years then have less materials for creating tau tangles? Also any thoughts on the protein ingested and how the protein was created (cooked etc.) prior to ingesting? Please could you comment?
I would only think that excessive consumption of non-essential amino acids along with a diet deficient in essential amino acids would lead to prolonged states where the body must convert and steal non—essential aminos to make essentials therefore robbing those necessary aminos from the process of making proline.
Getting “enough” essential amino acids and proline in highly bioavailable forms would seem to be key. Perhaps not too much but enough for certain. Starving the body of dietary proline and the necessary building block amino acids for proline would likely become a worse issue than slight excess.
So intriguing. It’s like you found a burned down house, then found blackened wood frames, then ran billions of scenarios, to find out which scenarios would produce blackened wood!
Too bad that the negative effects of free radicals on proline protein as an antioxidant was not mentioned. proline is an amino acid not a protein. Please let the people that make research for years work Apparently Proline is key. Although Proline is a non-essential amino acid, meaning the body can make it, perhaps that process is energetically expensive or perhaps becomes broken in people who starve themselves of dietary proline forcing the body to rob and convert other amino acids to make it.
Therefore, wouldn’t consuming enough bioavailable proline be the most likely solution?
A dietary chronology comes to mind here. We were diabolically told to stop eating red meat, cholesterol (eggs) and saturated animal fats which led to the influx of seed oils and animal replacement proteins. People started starving themselves of the best sources of proline, collagen and essential cholesterol like meat, chicken skin, eggs and bone broth which includes all of those proline rich, knuckles, joints, ligaments and tendons that humans once prized in their recipes.
There is a small amount of proline in some vegetable matter but meat, dairy and eggs are truly rich in the amino acids that are also in the biologically similar ratios to humans and in easily digestible and bioavailable forms. On the other hand, I would think that forcing the body to convert plant based amino acids that are in ratios not similar to human biology might create eventual proline conversion inefficiencies and deficiencies.
Proline is a protective agent; however, leucine takes away this protection. Even if leucine is good for muscle synthesis, it is bad for overall health. Proteins are recycled if not much protein is eaten. Mutation or formation of Tau Proteins cannot occur in low protein diets and sufficiently intense exercise. High protein is bad according to Dr. John Campbell, Dr. Dan Zatarski, Dr. Valter Longo, Dr. Ron Rosdale, Dr. Tim Spector and others)
Very interesting. Thank you. My first thought when I heard “seed” was that indeed the protein fibers seem Prionics. My second thought was that inflammation plays a big role which means the immune system is very much involved in various forms of dementia. It would not surprise me if later research was to reveal that individuals with early onstage dementia in addition to the substitution mutation of proline to leucine also have disrupted immunological response to infection/damage.
If you recall in use of ChAdOx1 as an adjuvant, it elicited an immunological response, forming clumps in a small subset of individuals. Since your computer simulations showed that at higher temperatures more space was created for misfolded strains, please pursue the possibility that brain inflammation following repeated infections over a lifetime may lead to the fibril/misfolded plaques and disrupt the hairpin formation.
Sensible, but my guess is that limiting your leucine intake with the hope of preventing aggregation of tau is unlikely to make a difference, because when your cells make tau they will use whatever leucine is available, not proline instead of leucine. Besides, your cells need leucine for innumerable other uses, so you probably don’t want your diet to be too leucine deprived.
APOE4 carriers are prone to HSV-1 outbreaks because their APOE contains more arginine which HSV-1 metabolizes. Plant based proteins (usually contain more arginine than lysine) make them more prone to HSV-1 outbreaks, just saying.
Thanks. 26:28
See the 2024 study headed by Dr. Dean Ornish.
Plant based eating is both preventative and healing.
In the book The China Study.
Higher protein diets from red meat were associated with cancer vs lower protein diets. The key is to eat plant-based protein. More and more research nowadays show that plant-based diets can be protective from Alzheimer’s. Good gut microbiome promotes proline synthesis in our bodies. Studies found that vegans as a whole have the best gut bacteria. Legumes, nuts, mushrooms and many other plants are good dietary sources of proline.
24:28 extra Prolines are added to the Spike mRNA encodings in the covid vaccine, so it does not change shape, as well. Proteins are large biomolecules that play critical roles in a host of cellular processes, from cell signaling to regulating the immune system.
However, these life-giving proteins can form toxic aggregate species that have been linked to several neurodegenerative diseases, including Alzheimer’s Disease and Parkinson’s Disease. In this program, UC Santa Barbara professor Joan-Emma Shea discusses the tau protein as a model system to study neurodegeneration.
Joan-Emma Shea says this protein plays a functional role in stabilizing microtubules in brain cells, but it can also self-assemble to form amyloid fibrils (large “clumps” of Tau proteins). There are several neurodegenerative diseases linked to tau assembly, including Alzheimer’s Disease, Pick’s Disease, and chronic traumatic encephalopathy, and they are collectively known as tauopathies. Shea discusses new insights into tauopathies and targets for therapeutics. Recorded on 06/26/2024. [10/2024] [Show ID: 40083]
Yes, fluoride from drinking and bathing water can inhibit the synthesis and metabolism of proline, although this effect is indirect and related to its interference with certain enzymes. Fluoride has been shown to inhibit the activity of enzymes that are dependent on cofactors like magnesium or zinc, as well as those involved in the citric acid cycle (Krebs cycle), such as aconitase. Proline synthesis depends on intermediates from the citric acid cycle (e.g., glutamate), so disruption of this cycle can indirectly affect proline production.
In particular:
1. Enzyme Inhibition: Fluoride inhibits enzymes like aldolase and enolase, which can disrupt glycolysis and energy metabolism, leading to downstream effects on amino acid biosynthesis.
2. Collagen Synthesis: Fluoride can reduce the availability of proline, which is essential for collagen synthesis, potentially affecting connective tissue health. This interaction is one of the reasons fluoride toxicities is associated with skeletal and connective tissue disorders when exposure is excessive.
NOTE: A person I knew with neurodegeneration abused alcohol, sugar, soft drinks addiction
Stress shrinks your brain. Neuroscientist Lisa Genova Author and Neuroscientist and the name of her book is Remember: The Science of Memory and The Art of Forgetting. explains how to strengthen it. Subscribe to Big Think on YouTube ► New to Big Think? Start here.
Up next, ► • 5 ways to build an Alzheimer’s-resistant brain | Lisa Genova – YouTube It may not feel like it when you can’t find your phone or “lose” your sunglasses sitting atop your head, but your memory is an amazing ability — and one we want to protect.
So it’s little wonder that any blips or blank spaces can send us spiraling into concern. Some recall issues here and there are normal, says neuroscientist and author Lisa Genova, and not every lapse means looming problems. (And don’t worry, forgetting names is a surprisingly tough thing for our brains to do!)
But, Genova says, there’s ways we can improve our memory, increase resilience and recall and be more comfortable with ourselves and our minds. From making lists and getting Google’s help to giving yourself a pop quiz, getting some meditation in, and just plain paying attention, these tips will have your steel trap gleaming. Read the video transcript ► 9 tactics to build a stronger memory and mind – Big Think
Sing a song to the joy of research. Cure? Theories?
How about a Retired Marine in Every School ► Highly Lethal Weapons 202411 – Mark V1
Research shows protein-rich diets may influence gut microbiome and body composition
How to improve your Gut Health: An Introduction to Functional Medicine
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TIMESTAMPS 
Intro 0:22 Meet Pete and His Approach as a Functional Medicine Doctor 1:35 The Treatment: What we are about to do today and what you need to consider 3:17 The Bioresonance Test 3:33 Testing: Sensitivity towards Bacteria 3:43 What is the Preferential Mode in Functional Medicine? 3:50 What is Switching in Functional Medicine? 4:04 Testing: Foods, Metals, and Immune Challenges 4:22 What is Organ Testing in Functional Medicine? 4:38 Dosage Calculating in Functional Medicine 4:53 Testing: Vitamins 5:07 Testing: Food 5:23 What is Organ Manipulation in Functional Medicine? 6:21 Why I reached out to Pete and tried Functional Medicine – Arthritis & High Cholesterol 7:02 The Role of Functional Medicine in Gut Health 7:46 What is Epigenetics? 8:21 The Role of Frequencies in Functional Medicine
The Link Between Proteins, Alzheimer’s and Parkinson’s Diseases
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