In a breakthrough discovery at the Children’s Medical Center Research Institute at UT Southwestern (CRI), a research team led by Ralph DeBerardinis, M.D., Ph.D., has taken a significant step in cracking the code of an atypical metabolic pathway that allows certain cancerous tumors to thrive, providing a possible roadmap for defeating such cancers.
Published in Cell Reports, andfollowing up on Dr. DeBerardinis’ landmark finding in 2011, this most recent discovery identifies the triggering mechanism that plays a key role in causing a series of energy-generating chemical reactions known as the Krebs cycle to run in reverse.
“With this finding, we have learned there are particular enzymes that work together to enable the reverse pathway to function, much like the tiny gears that turn in opposite directions to power a mechanical clock,” said Dr. DeBerardinis, director of CRI’s Genetic and Metabolic Disease Program and associate professor in the Department of Pediatrics and the Eugene McDermott Center for Human Growth and Development at UT Southwestern Medical Center.
The identification of the mechanism could provide a future target for drugs that would attack tumors relying upon the reverse pathway for sustenance and growth. Tumors of this type, often found in the brain, lungs and kidneys, tend to be difficult for oncologists to treat because cells using the atypical pathway seem to resist existing treatments like chemotherapy.
“Prior to this discovery, we didn’t have enough information about how to tap into the reverse metabolic pathway without disrupting the pathways that were operating in the typical, forward manner,” said Dr. DeBerardinis, senior author of the study. “We now believe there is a specific enzyme critical to the reverse pathway that can be deleted without impairing normal function. If we can eliminate that enzyme, we may be able to starve tumors of their supply of building blocks for growth.”
With the confusion and contradiction is science and the medical profession.
Cracking the cancer’s code isn’t easy. Increasingly, modern cancer research is turning into a form of code-breaking. But with cancer, we are still learning the language. Cancer is a disease of our DNA – the molecule that contains all the instructions we need to be us. It is written using a string of four chemicals, represented by the letters A, T, C and G, and this code stands at more than three billion ‘letters’ long. And it’s the faults in this code that lead to cancer. .
In cancer, metabolic reprogramming through the alteration of oncogenic signaling pathways is viewed as an essential component of malignancy.
Research in cancer metabolism is motivated by the hope that understanding the basis of metabolic reprogramming will stimulate development of new approaches in cancer imaging and therapy, both of which have historically capitalized on altered metabolic states in tumors.
Cancer cells use abundant nutrients like glucose, glutamine and lipids to feed metabolic pathways that sustain energetics, biosynthesis, and redox homeostasis. Our understanding of the relative importance of cell-autonomous and non-cell autonomous influences on metabolic reprogramming is far from complete.
Despite the fact that we’re still by no means fluent in ‘DNA’, we’re making progress, piecing together a basic phrase book, and moving on to more sophisticated sentences. International projects like The Cancer Genome Atlas and the International Cancer Genome Consortium are collating the DNA code from thousands of cancer patients.
https://www.youtube.com/watch?v=pxShRq0cg24&t=4s https://www.youtube.com/watch?v=aGiEvvJPyeA&t=4s https://www.youtube.com/watch?v=29aWm03y57Y
My good friend Doris Parreno states, the main reason I survived cancer is because I had the confidence to research, study, implement and encompassed all aspects of healing and used common sense…. if you never clean a house in 50 years. 
A lot of people look for the magic pill approach which is what is promoted by the system…. true healing is all encompassing….not a magical oil or pill…. proper hydration, water, nutrients, detox, reduce stress…not every body wants to do what it takes…. it’s not easy. http://www.solitarius.org/2014/07/03/testimony-health-schedule-links/CONFIRMED: Cancer is entirely a man-made disease. Your Lifestyle Causes Cancer NOT Your Genetics.
This would mean, we are able to lower our risks of developing cancer by changing our lifestyle and establishing healthier habits.
While the FDA continues to search for a cure, there are many natural cures and treatments for cancer.
•The Budwig Protocol: Dr. Johanna food plan for cancer allows you to enjoy many of your favorite recipes while at the same time maintaining a balanced and healthy diet. The principle factor to keep in mind is that now you choose quality food products and natural ingredients. There are many websites that talk about Dr. Budwig food recommendations, however not all of them are accurate. In this interview with Carl O. Helvie Klaus Pertl tells The 3E-Centre is the only centre world wide that offers the „original“ and „strict“ Budwig Diet for people with cancer. https://www.holistichealthshow.com/wordpress/tag/klaus-pertl-germany/
Hemp oil: is made from the flowering buds of the marijuana plant. Making hemp oil is very simple and there are multiple videos on You Tube showing you how to make your own.
•Gerson Natural Therapy: Dr. Gerson believed cancer would not live in body that had a balanced, properly functioning liver. He discovered that he could cure the majority of cancers by changing the diet. This meant eating a vegan diet (avoiding meat and dairy), with low salt and drinking freshly juiced fruits and vegetables 10 times everyday. Coffee enemas were recommended as part of the treatment for pain relief and detoxification, done 3 to 4 times everyday.
There is a Gerson clinic in Mexico. This is one of the best cancer alternative treatments.
•Antineoplastins: Dr. Stanislaw Burzynski holds a doctorate in biochemistry and is an MD. This doctor is recognized internationally as a scientist and physician who discovered and developed treatment of cancers with biologically active peptides. He discovered that people who have cancer were missing these peptides in their urine and blood. People who do not have cancer have these peptides. Since 1967 from his clinic in Houston, Texas, Dr. Burzynski has treated over 50 types of cancers effectively. The best successes have been with cancers of the ovaries, lungs, colon, prostate, neck and head, breast and non-Hodgkin’s lymphoma. He has possibly discovered the most successful FDA approved drug therapy for cancer ever and his antineoplastins (which have no toxic side effects) significantly outperform any chemotherapy treatment, making it one of the best cancer alternative treatments.
•Pancreatic enzymes: Dr. William Kelley developed a highly effective natural protocol for treating advanced cancers. He did this with pancreatic enzymes and other nutritional substances.
In his second year of med school, Dr. Gonzalez met Dr. Kelley and took five years to research Dr. Kelly’s patient records spaning thousands of patients. After personally interviewing many of these patients, finding them all in good health, Dr. Gonzalez realised something very important was occuring. Today Dr. Gonzalez has refined and improved on Dr. Kelley’s original discoveries giving each patient an individualized diet with supplements and large quantities of enzymes. Coffee enemas, juice fasts and liver flushes are utilized for detoxification.
Dr. Gonzalez graduated from Brown University. He finished his pre-med studies at Columbia University and then went to medial school at Cornell Medical College where he was given the honor of Teagle Scholar. He has received many awards for his excellence in internal medicine and cancer imunology research. He also was recipient of the Ernst L. Wynder Award from the Center for Mind-Body Medicine in 2000.
•Salve treatments: a salve made from bloodroot is used as an alternative treatment for skin cancers. Some names for this are Black Salve, Indian Mud and Compound X. Bloodroot salve will draw the tumors from your body out through the skin, healing underneath as the mass falls out.
•Energy healing: specially trained practitioners heal by projecting energy known in Chinese medicine as Chi or Qi. They use a sonogram so you can see cancer tumors dissolve before your eyes while the practitioners “work” on patients in a Beijing hospital .
•LifeOne: active herbal ingredients include selenium methionine, green tea extract, quercetin, turmeric, resveratrol, diindolymethane, versicolor, coriolus and chrysin.
•Cesium Chloride: is the most alkalline mineral salt in nature and is non-toxic. It has been a medical treatment since the 1800s and has been used successfully in treating some cancer patients since the 1980s. It is also known for its ability to remove the pain of cancer. This would be a great addition the the Alkaline diet.
•Alkaline diet: The metabolism of cancer cells has a very narrow pH tolerance, if you can interfere with cancer cell metabolism, you can theoretically stop cancer. The proposed alkaline therapy for people is a “high pH therapy” and has been developed to normalize the intracellular pH of the cancer, while increasing the pH of cancer cells to a range above 7.5. According to published research, it is at that pH they experience cell death and revert to normal.
The alkaline diet, which is primarily plant-based and avoids sugar, dairy, wheat and other high-gluten grains. Emphasizing fresh vegetables and vegetable juices along with cruciferous vegetables and greens, changes the body’s intracellular pH.
•Essiac Tea: is a long proven method of curing cancer since the 1920s and before.
Named by Rene Caisse (“caisse” spelt backwards), the tea consists of four main herbs that grow in the wilderness of Ontario, Canada. The original formula is believed to have its roots from the native Canadian Ojibway Indians.
The four main herbs that make up Essiac are Burdock Root, Slippery Elm Inner Bark, Sheep Sorrel and Indian Rhubarb Root.
While the basic components of Essiac are well known, the exact proportions of the herbs in Essiac are the matter of much speculation. The cancer patient should be concerned with the quality of the herbs, and the quality of the processing.
Sheep Sorrel is the main cancer killing herb in Essiac. Sheep Sorrel has been known about for over a hundred years as a cancer fighting herb.
•Whole foods diet: Dr. John McDougall, MD a board certified internist suggests a whole diet. Our diet with 42% of calories coming from fat and the rest of the food processed and devitalized. Animal foods create an acidic pH blood which promotes cancers. Cancer cells feed on sugar and we have gone from a person eating 5 pounds of sugar in a year in 1920 to 150 pounds per person per year! High fructose corn syrup is cancer sugar. Cancer was somewhat rare at the turn of the 20th century. Now 100 years later 1 in 2 people will have cancer.
•Beta glucan: is the most potent immune system enhancer and immunomodulator (more potent and effective than interferon). In Asia, beta glucan is a primary treatment for all types of cancer with over 3,000 published medical studies to support its use.
•Maitake Mushroom (Grifola): Clinical researchers at the National Cancer Center in Japan reports in approximately 80% of animals with cancer who were given maitake mushroom extracts had total elimination of tumors.
•Laetrile (vitamin B17): is the most amazing cure for cancer, and it has been known about for over 35 years. It reacts with cancer cell enzymes to form hydrogen cyanide that destroys the cancer cells on contact. It does this without damaging any of the healthy cells. There are a number of clinics in Tiajuana, Mexico who perform this treatment.
•Carctol: Dr. Rosy Daniel believes Carctol, an East Indian ayurvedic herbal formula, could well be a cure for cancer. The formula was originally put together by Dr. Nandlal Tiwari of Rajasthan, India. He has been treating patients with cancer using this for over twenty years. Dr. Tiwari has case files of 1,900 people who were treated with Carctol were considered to be beyond medical help. According to his records, one fourth of the patients had a 75 to 100 percent improvement. One third reported up to a 75% improvement. Carctol seems to be particularly effective in treating and curing blood cancers and gastro-intestinal cancers.
•Dichloroacetic Acid (DCA): A researcher and professor, Dr. Evangelos Michelakis, has demonstrated that DCA (a small non-toxic molecule) causes reduction in a number of cancers including brain, breast and lung. Remember to supplement for neuropathy 🙂
Dr. Michelakis and Dr. Sebastien Bonnet, published the findings of their research in the medical journal Cancer Cell. Doctors and medical scientists have used DCA for many decades as a treatment for metabolism errors in children that occur with mitochondrial diseases and has been associated with cancer since the 1930s.
“I think DCA can be selective for cancer because it attacks a fundamental process in cancer development that is unique to cancer cells,” Michelakis said. “One of the really exciting things about this compound is that it …. might be able to treat many different forms of cancer.”“If there were a single magic bullet, though, it might be something like dichloroacetate, or DCA…”
Newsweek, January 23, 2007
•Dendritic Cell Therapy: Cancer cells have defenses against the body’s immune system. The cancer cells are undetectable by our immune system. Cancer cells also prevent normal immune activity which stops any attacks. Dendritic cell therapy destroys these cancer cell defenses allowing the body to make an immune offense to recover. One clinic that offers this is the BioPulse Clinic in Tijuana, Mexico.
•Iscador: is made from certain fermented extracts of the European mistletoe plant. It has been utilized by physicians in Europe since 1920. There are 5,000 case studies on the success in treating cancer with Iscador. There have been two scientific reviews of Iscador clinical research and both have stated that Iscador’s effectiveness as a therapy for cancer is clearly supported by these findings:
-After 3 years, the survival rate for patients with skin cancer who took Iscador was 80 % compared to 65 % for those not taking it
-75 % of bronchial cancer patients taking Iscador were living after 4 years compared to only 35 % of those not taking it
-People with bladder papillomas not taking Iscador experienced a malignancy rate of 50 % while the rate for those taking Iscador was 14 %
-An 83 % five year survival rate for women with cervical cancer if they had surgery, radiation and Iscador while the rate was 69 % for those who had radiation alone
-A significantly larger number of women with breast cancer treated with Iscador were doing well after 10 years than those who had none
•High-dose of Vitamin C intravenously: Since the 1970s, high-doses of vitamin C has been studied as a treatment cancer. Some studies of high-dose vitamin C through an IV, in cancer patients have shown improved quality of life, as well improvements in physical, mental, and emotional functions, symptoms of fatigue, nausea and vomiting, pain, and appetite loss with very little side effects.
http://livingtraditionally.com/
Documentary Film is a broad category of visual expression that is based on the attempt, in one fashion or another, to document reality. Knowledge comes in many different ways through our five senses. Hearing, watching, touching, smelling and tasting are the only doorways to the outer world. The wise men say that if something is not truly experienced with all our five senses, the experience will be partial, not total. Therefore in a way almost all our gained knowledge through life is partial. And maybe they are right
Preview PBS Nova Documentary Collection: Cracking the Code Of Life
